ea0020p657 | Reproduction | ECE2009
Masha Andi
, Manieri Chiara
, Dinatale Stefano
, Bruno Guido Albino
, Ghigo Ezio
, Martina Valentino
Introduction: Nitric oxide (NO) plays a wide spectrum of biological actions including a positive role in oocyte maturation and ovulation. Free radicals have been shown elevated in PCOS and therefore would be responsible for quenching NO that, in turn, would play a role in determining oligo or amenorrhea connoting PCOS. We recently demonstrated that the combined administration of N-acetylcysteine (NAC) and arginine (ARG) is able to exert an antioxidant action leading to ...